Which of the following statements correctly describes the significance of the given picture?

1. The painting represents Leonardo da Vinci's belief in the connection between art and science.
2. The painting showcases da Vinci's study of religious symbolism in the Renaissance.
3. The painting demonstrates da Vinci's use of light, shadow, and detail to achieve realism.
4. The painting reflects da Vinci's architectural skills.

Which empire had Constantinople as its capital, and when was it captured by the Turks?

Name two sculptors of the Renaissance period and one creation by each.

Read the following excerpt and answer the question that follows:

"The invention of the printing press also played a role in the emergence of the Renaissance in the continent and in England."

(Source: https://egyankosh.ac.in/bitstream/123456789/22151/1/Unit-8.pdf)

When and where was the printing press invented?